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The Position of Exosome MicroRNA-103 within the Proliferation and Invasion of Hepatoma Cells and Its Mechanism


MicroRNA-103 and Invasion of Hepatoma



Yushi Lin

Division of Laboratory, Weihaiwei Individuals’s Hospital, Weihaiwei, 264200, China


Fengmei Shi

Division of Laboratory, Weihaiwei Individuals’s Hospital, Weihaiwei, 264200, China


Junyao Yan

Division of Surgical procedure, Weihaiwei Individuals’s Hospital, Weihaiwei, 264200, China


Zhongyuan Sui

Division of Surgical procedure, Weihaiwei Individuals’s Hospital, Weihaiwei, 264200, China


Bo Solar

Division of Surgical procedure, Weihaiwei Individuals’s Hospital, Weihaiwei, 264200, China


Guangwei Xu

Division of Laboratory, Weihaiwei Individuals’s Hospital, Weihaiwei, 264200, China

Corresponding Writer(s) : Guangwei Xu

tairenguai53957@163.com

Mobile and Molecular Biology,
Vol. 68 No. 5: Situation 5

Summary

Liver most cancers (HCC) is a typical malignant tumor whose incidence is rising worldwide, however present chemotherapeutic brokers aren’t ideally efficient medication and have appreciable resistance to chemotherapy. Exosome microRNA-103 performs an necessary function within the proliferation and invasion of liver most cancers cells. The aim of this text is to analyze the function and mechanism of exosome microRNA-103 in hepatocellular carcinoma cell proliferation and invasion. 84 sufferers with hepatocellular carcinoma recognized in a hospital from June 2017 to June 2020 had been chosen. The common age was 60.13±6.99 years. When the affected person was fasting, 3 mL of peripheral venous blood was taken. And 50 wholesome management teams had been established, with a median age of 59.98±8.18 years outdated. 3 ml of peripheral venous blood was collected on an empty abdomen to match the cell proliferation price and invasion price. The outcomes of the examine confirmed that the variety of stage III hepatocellular carcinoma cells invaded at 6h was 68.9, and it modified to 89.4 at 12h, and 106.4 at 24h; in contrast with that, the cell invasion price in stage IV was increased. The variety of stage IV hepatocellular carcinoma invasions at 6h was 68, which modified to 94.5 at 12h and 112.4 at 24h.

Key phrases

exosome microRNA-103
liver most cancers cells
cell proliferation
mechanism analysis

Lin, Y., Shi, F., Yan, J., Sui, Z., Solar, B., & Xu, G. (2022). The Position of Exosome MicroRNA-103 within the Proliferation and Invasion of Hepatoma Cells and Its Mechanism: MicroRNA-103 and Invasion of Hepatoma. Mobile and Molecular Biology, 68(5), 47–53. https://doi.org/10.14715/cmb/2022.68.5.6

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